Mannitol interactions
Full monograph for MannitolCheck it against another medicine
Medicines
333 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Amikacin | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Betamethasone + Clotrimazole + Gentamicin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Betamethasone + Neomycin Sulphate (Ophthalmic) | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Cinchocaine + Hydrocortisone + Framycetin + Esculin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Cinchocaine + Hydrocortisone + Neomycin + Esculin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Clobetasol Propionate + Neomycin Sulphate + Nystatin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Dexamethasone + Neomycin + Glacial Acetic Acid | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Dexamethasone + Tobramycin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Fluocinolone Acetonide + Neomycin Sulfate | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Fluormetholone + Neomycin Sulphate | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Fluorometholone + Gentamicin | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Gentamicin + Hydrocortisone Acetate | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Gentamicin SulfateInjectionOphthalmic | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Gramacidin + Neomycin + Polymixin B | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Hydrocortisone + Neomycin Sulphate + Polymixin B | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Hydrocortisone Acetate + Neomycin Sulphate | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Kanamycin | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Loteprednol Etabonate + Tobramycin | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…3 documented mechanisms | 19 sources — open the full entry |
| Monobasic Sodium Phosphate + Dibasic Sodium Phosphate | Major | Others | The following interaction applies only to products containing sodium biphosphate that are used for bowel cleansing. It does not apply to products containing… | 3 sources — open the full entry |
| Neomycin Sulfate + Bacitracin Zinc | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Neomycin Sulfate + Bacitracin Zinc + Polymyxin B Sulfate | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Neomycin Sulphate + Polymyxin B Sulphate + Pramoxine | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Prednisolone + Neomycin Sulphate + Polymixin B Sulphate | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| TobramycinNebuliser SolutionOphthalmic | Major | Synergy | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or… | 19 sources — open the full entry |
| Triamcinolone + Neomycin + Nystatin + Gramicidin | Major | Synergy · Unknown | Coadministration of parenteral or inhaled aminoglycoside antibiotics or oral neomycin in combination with loop diuretics may potentiate the risk of oto- or…2 documented mechanisms | 19 sources — open the full entry |
| Aclidinium Bromide + Formoterol Fumarate | Moderate | Synergy | Coadministration with beta-2 adrenergic agonists may potentiate the hypokalemic effects of potassium-wasting diuretics. Beta-2 agonists can cause clinically… | 8 sources — open the full entry |
| Aluminium Hydroxide + Magnesium Hydroxide | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Aluminium Hydroxide + Magnesium Hydroxide + Simethicone | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Amlodipine Besilate + Benazepril Hydrochloride | Moderate | Synergy · Unknown | Although they are frequently combined in clinical practice, diuretics and angiotensin converting enzyme (ACE) inhibitors may have additive effects…2 documented mechanisms | 26 sources — open the full entry |
| Arformoterol Tartrate | Moderate | Synergy | Coadministration with beta-2 adrenergic agonists may potentiate the hypokalemic effects of potassium-wasting diuretics. Beta-2 agonists can cause clinically… | 8 sources — open the full entry |
| Atracurium Besilate | Moderate | Synergy | Diuretics may induce hypokalemia and prolong the neuromuscular blocking effects of nondepolarizing muscle relaxants. | 4 sources — open the full entry |
| Beclometasone + Formoterol + Glycopyrronium | Moderate | Synergy | Coadministration with beta-2 adrenergic agonists may potentiate the hypokalemic effects of potassium-wasting diuretics. Beta-2 agonists can cause clinically… | 8 sources — open the full entry |
| Beclomethasone Dipropionate + Formoterol Fumarate | Moderate | Synergy | Coadministration with beta-2 adrenergic agonists may potentiate the hypokalemic effects of potassium-wasting diuretics. Beta-2 agonists can cause clinically… | 8 sources — open the full entry |
| Bisacodyl | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Budesonide + Formoterol Fumarate | Moderate | Synergy | Coadministration with beta-2 adrenergic agonists may potentiate the hypokalemic effects of potassium-wasting diuretics. Beta-2 agonists can cause clinically… | 8 sources — open the full entry |
| Budesonide + Glycopyrronium Bromide + Formoterol Fumarate | Moderate | Synergy | Coadministration with beta-2 adrenergic agonists may potentiate the hypokalemic effects of potassium-wasting diuretics. Beta-2 agonists can cause clinically… | 8 sources — open the full entry |
| Calamine + Zinc Oxide + Glycerine | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Canagliflozin Hemihydrate | Moderate | Synergy | Sodium-glucose co-transporter 2 (SGLT-2) inhibitors may potentiate the hypotensive effects of diuretics and other antihypertensive agents or vasodilators… | 15 sources — open the full entry |
| Captopril | Moderate | Synergy | Although they are frequently combined in clinical practice, diuretics and angiotensin converting enzyme (ACE) inhibitors may have additive effects… | 26 sources — open the full entry |
| Carbamazepine | Moderate | Synergy | Carbamazepine may cause clinically significant hyponatremia. Data show that the risk of hyponatremia may be additive when carbamazepine and hydrochlorothiazide… | 5 sources — open the full entry |
| Carboxymethylcellulose Sodium + Glycerin | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Cisatracurium Besylate | Moderate | Synergy | Diuretics may induce hypokalemia and prolong the neuromuscular blocking effects of nondepolarizing muscle relaxants. | 4 sources — open the full entry |
| Citalopram Hydrobromide | Moderate | Synergy | Coadministration with diuretics may potentiate the risk of hyponatremia associated with the use of selective serotonin reuptake inhibitors (SSRIs) and… | 57 sources — open the full entry |
| Dapagliflozin Propanediol | Moderate | Synergy | Sodium-glucose co-transporter 2 (SGLT-2) inhibitors may potentiate the hypotensive effects of diuretics and other antihypertensive agents or vasodilators… | 15 sources — open the full entry |
| Desvenlafaxine Succinate | Moderate | Synergy | Coadministration with diuretics may potentiate the risk of hyponatremia associated with the use of selective serotonin reuptake inhibitors (SSRIs) and… | 57 sources — open the full entry |
| Digoxin | Moderate | Synergy | Although diuretics and digitalis glycosides are frequently and appropriately used together, diuretic-induced hypokalemia and hypomagnesemia may predispose… | 10 sources — open the full entry |
| Diroximel Fumarate | Moderate | Synergy | The use of fumaric acid esters in combination with medications that can cause nephrotoxicity (e.g., aminoglycosides, diuretics, nonsteroidal anti-inflammatory… | 7 sources — open the full entry |
| Duloxetine Hydrochloride | Moderate | Synergy | Coadministration with diuretics may potentiate the risk of hyponatremia associated with the use of selective serotonin reuptake inhibitors (SSRIs) and… | 57 sources — open the full entry |
Conditions
Conditions in which Mannitol needs care, as documented in this source.
Dehydration
MajorThe use of osmotic diuretics is contraindicated in patients with anuria, severe dehydration, pulmonary edema, or severe cardiac decompensation. An increase in the tonicity of the blood may occur in these patients that could exacerbate these conditions.
2 sources
- "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc (2001):
- "Product Information. Ismotic PB (isosorbide)." Alcon Laboratories Inc (2001):
Dehydration
ModerateThe use of osmotic diuretics is associated with an increase in blood tonicity. Osmotic diuretics should be administered cautiously in patients with confused mental states, diabetes, congestive heart failure, severe dehydration, and cardiac, renal, or hepatic disease.
2 sources
- "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc (2001):
- "Product Information. Ismotic PB (isosorbide)." Alcon Laboratories Inc (2001):