Ethinyl Estradiol + Gestodene interactions
Checked as Ethinylestradiol in this data source.
Full monograph for Ethinyl Estradiol + GestodeneCheck it against another medicine
Medicines
330 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Bosentan Monohydrate | Major | Metabolism | RECOMMENDED: Coadministration with bosentan may decrease the plasma concentrations and efficacy of contraceptive hormones. The mechanism is bosentan induction… | 83 sources — open the full entry |
| Brigatinib | Major | Metabolism | RECOMMENDED: Coadministration with brigatinib may decrease the plasma concentrations of contraceptive hormones. Brigatinib has been shown in vitro to induce… | 37 sources — open the full entry |
| Carbamazepine | Major | Metabolism | RECOMMENDED: Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may… | 65 sources — open the full entry |
| Carfilzomib | Major | Synergy | Venous thromboembolic events, including deep vein thrombosis (DVT) and pulmonary embolism (PE), have occurred during treatment with carfilzomib, and concurrent… | 38 sources — open the full entry |
| Dantrolene Sodium | Major | Synergy | The use of estrogens may potentiate the risk of hepatotoxicity associated with dantrolene therapy. The mechanism of interaction is unknown. Fatal and non-fatal… | 39 sources — open the full entry |
| Fosphenytoin Sodium | Major | Metabolism | RECOMMENDED: Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may… | 65 sources — open the full entry |
| Glecaprevir + Pibrentasvir | Major | Metabolism · Synergy | Coadministration of ethinyl estradiol with glecaprevir-pibrentasvir may increase the risk of alanine aminotransferase (ALT) elevations. ALT elevations are also…2 documented mechanisms | 5 sources — open the full entry |
| Griseofulvin [Ultra Microsize] | Major | Metabolism | RECOMMENDED: Limited clinical data suggest that griseofulvin may reduce the efficacy of contraceptive hormones. The proposed mechanism is accelerated clearance… | 48 sources — open the full entry |
| Lenalidomide | Major | Synergy | Concomitant treatment with agents that can cause thrombosis such as estrogens may potentiate the risk of venous thromboembolic events associated with the use… | 36 sources — open the full entry |
| Mavacamten | Major | Metabolism | Coadministration with mavacamten may decrease the plasma concentrations and efficacy of contraceptive hormones. The proposed mechanism is mavacamten induction… | 1 sources — open the full entry |
| Mycophenolate Mofetil | Major | Others | RECOMMENDED: Coadministration with mycophenolic acid may decrease the plasma concentrations and, theoretically, the efficacy of contraceptive hormones. The… | 37 sources — open the full entry |
| Mycophenolic acid | Major | Others | RECOMMENDED: Coadministration with mycophenolic acid may decrease the plasma concentrations and, theoretically, the efficacy of contraceptive hormones. The… | 37 sources — open the full entry |
| Oxcarbazepine | Major | Metabolism | RECOMMENDED: Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may… | 65 sources — open the full entry |
| Phenobarbital | Major | Metabolism | RECOMMENDED: Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may… | 65 sources — open the full entry |
| Phenytoin Sodium | Major | Metabolism | RECOMMENDED: Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may… | 65 sources — open the full entry |
| Pomalidomide | Major | Synergy | Concomitant treatment with agents that can cause thrombosis such as erythropoiesis-stimulating agents, estrogens, selective estrogen receptor modulators, or C1… | 4 sources — open the full entry |
| Primidone | Major | Metabolism | RECOMMENDED: Coadministration with certain anticonvulsants such as carbamazepine, eslicarbazepine, oxcarbazepine, phenobarbital, phenytoin, and primidone may… | 65 sources — open the full entry |
| Relugolix | Major | Antagonism | Coadministration of hormonal contraceptives may decrease the efficacy of the fixed-dose oral formulation of relugolix, estradiol, and norethindrone when used… | 4 sources — open the full entry |
| Relugolix + Estradiol + Norethindrone | Major | Antagonism | Coadministration of hormonal contraceptives may decrease the efficacy of the fixed-dose oral formulation of relugolix, estradiol, and norethindrone when used… | 4 sources — open the full entry |
| Rifampicin | Major | Metabolism | RECOMMENDED: Coadministration with rifampin or other rifamycins may reduce the efficacy of contraceptive hormones. There have been numerous case reports of… | 113 sources — open the full entry |
| Rifampicin + Isoniazid | Major | Metabolism | RECOMMENDED: Coadministration with rifampin or other rifamycins may reduce the efficacy of contraceptive hormones. There have been numerous case reports of… | 113 sources — open the full entry |
| Rifampicin + Isoniazid + Pyrazinamide + Ethambutol | Major | Metabolism | RECOMMENDED: Coadministration with rifampin or other rifamycins may reduce the efficacy of contraceptive hormones. There have been numerous case reports of… | 113 sources — open the full entry |
| Thalidomide | Major | Synergy | Concomitant treatment with agents that can cause thrombosis such as estrogens may potentiate the risk of venous thromboembolic events associated with the use… | 40 sources — open the full entry |
| Tizanidine Hydrochloride | Major | Metabolism | Coadministration with oral contraceptives may significantly increase the plasma concentrations and pharmacologic effects of tizanidine. The proposed mechanism… | 41 sources — open the full entry |
| Tranexamic Acid | Major | Others | There are no clinical data on the use of tranexamic acid in combination with hormonal contraceptives. Because tranexamic acid is an antifibrinolytic agent… | 38 sources — open the full entry |
| Abametapir | Moderate | Metabolism | Based on in vitro inhibition data, a single topical application of abametapir lotion may increase plasma concentrations of drugs that are substrates of CYP450… | 1 sources — open the full entry |
| Acarbose | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Acyclovir + Hydrocortisone | Moderate | Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding… | 9 sources — open the full entry |
| Adalimumab | Moderate | Metabolism | Plasma concentrations of drugs that are CYP450 substrates may decrease following the initiation of interleukin (IL) inhibitors, tumor necrosis factor (TNF)… | 19 sources — open the full entry |
| Alogliptin Benzoate | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Amikacin | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Aminophylline | Moderate | Metabolism | The coadministration with contraceptive steroids may increase the plasma concentrations of theophylline and other methylxanthines. The proposed mechanism is… | 35 sources — open the full entry |
| Amoxicillin + Clavulanic Acid | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Amoxicillin Trihydrate | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Ampicillin Sodium | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Anastrozole | Moderate | Antagonism | Theoretically, estrogen-containing drugs may negate the pharmacologic effects of aromatase inhibitors in the treatment of hormone-dependent breast cancer… | 3 sources — open the full entry |
| Apalutamide | Moderate | Metabolism | RECOMMENDED: Coadministration with inducers of CYP450 3A4 may decrease the plasma concentrations of estrogens and progestins. Estrogens have been shown in in… | 50 sources — open the full entry |
| Aprepitant | Moderate | Metabolism | RECOMMENDED: Aprepitant and its prodrug, fosaprepitant, may reduce the efficacy of low-dose hormonal contraceptives during and for up to 28 days after… | 35 sources — open the full entry |
| Armodafinil | Moderate | Metabolism | RECOMMENDED: Coadministration with modafinil (the racemate) or armodafinil (the R-enantiomer) may decrease the plasma concentrations of ethinyl estradiol and… | 47 sources — open the full entry |
| Artemether + Lumefantrine | Moderate | Metabolism | RECOMMENDED: Coadministration with artemether may decrease the plasma concentrations of contraceptive hormones. The proposed mechanism is artemether induction…2 documented mechanisms | 39 sources — open the full entry |
| Asciminib | Moderate | Metabolism | Coadministration with asciminib may increase the plasma concentrations of drugs that are primarily metabolized by the CYP450 3A4 isoenzyme. The mechanism is… | 1 sources — open the full entry |
| Azithromycin DihydratebaseOphthalmic | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Aztreonam | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Bacitracin Zinc + Polymyxin B Sulfate | Moderate | Antagonism · Others | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…3 documented mechanisms | 74 sources — open the full entry |
| Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + Lidocaine | Moderate | Antagonism · Metabolism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…2 documented mechanisms | 46 sources — open the full entry |
| Benzathine Benzylpenicillin | Moderate | Antagonism | RECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most… | 38 sources — open the full entry |
| Betamethasone | Moderate | Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding… | 9 sources — open the full entry |
| Betamethasone + Calcipotriol | Moderate | Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding… | 9 sources — open the full entry |
| Betamethasone + Clotrimazole | Moderate | Metabolism · Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding…2 documented mechanisms | 17 sources — open the full entry |
| Betamethasone + Clotrimazole + Gentamicin | Moderate | Antagonism · Metabolism · Synergy | Estrogens may enhance the systemic effects of both endogenous and exogenous corticosteroids. The proposed mechanism is an increase in serum cortisol-binding…3 documented mechanisms | 55 sources — open the full entry |
Therapeutic duplication
Drug classes that overlap with Ethinyl Estradiol + Gestodene, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.
estrogens
The recommended maximum number of medicines in the 'estrogens' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'estrogens' category.
Example product in the source data (US market): Oriahnn
estrogens
The recommended maximum number of medicines in the 'estrogens' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'estrogens' category.
Example product in the source data (US market): Estradiol/norethindrone/relugolix