Ropivacaine Hydrochloride interactions
Checked as Ropivacaine in this data source.
Full monograph for Ropivacaine HydrochlorideCheck it against another medicine
Medicines
166 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Chloroquine Phosphate | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Cyclophosphamide | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Dapsone | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Hydroxyurea | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Ifosfamide | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Isosorbide Dinitrate + Hydralazine Hydrochloride | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Isosorbide Mononitrate | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Lidocaine + Prilocaine | Major | Synergy | Prilocaine can cause dose-related methemoglobin formation via its ortho-toluidine metabolite. Coadministration with other oxidizing agents that can also induce…3 documented mechanisms | 14 sources — open the full entry |
| Metoclopramide Hydrochloride | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Nitrofurantoin | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Nitrofurantoin + Nitrofurantoin Microcrystals | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| NitroglycerinbaseIV InfusionOintment | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Phenobarbital | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Phenytoin Sodium | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Primaquine Phosphate | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Quinine Sulfate | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Sulfasalazine | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine… | 5 sources — open the full entry |
| Sulphamethoxazole + Trimethoprim | Major | Synergy | Coadministration of local anesthetics with other oxidizing agents that can also induce methemoglobinemia such as antimalarials (e.g., chloroquine, primaquine…2 documented mechanisms | 5 sources — open the full entry |
| Abametapir | Moderate | Metabolism | Based on in vitro inhibition data, a single topical application of abametapir lotion may increase plasma concentrations of drugs that are substrates of CYP450… | 1 sources — open the full entry |
| Alprazolam | Moderate | Synergy | The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants. | 7 sources — open the full entry |
| Amiodarone Hydrochloride | Moderate | Synergy | Amide-type local anesthetics may have additive cardiac effects (e.g., bradycardia, chest pain, heart block, arrhythmias, ECG abnormalities, cardiac arrest)… | 2 sources — open the full entry |
| Amitriptyline Hydrochloride + Chlordiazepoxide | Moderate | Synergy | The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants. | 7 sources — open the full entry |
| Artemether + Lumefantrine | Moderate | Metabolism | Coadministration with lumefantrine may increase the plasma concentrations of drugs that are substrates of the CYP450 2D6 isoenzyme. In vitro, lumefantrine…2 documented mechanisms | 5 sources — open the full entry |
| Articaine Hydrochloride + Epinephrine Bitartrate | Moderate | Synergy · Unknown | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics.2 documented mechanisms | 1 sources — open the full entry |
| Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + Lidocaine | Moderate | Metabolism · Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics.3 documented mechanisms | 8 sources — open the full entry |
| Benzocaine + Butamben + Tetracaine Hydrochloride | Moderate | Synergy | Some topical anesthetics can be systemically absorbed and cause methemoglobinemia, particularly when applied to mucous membranes. Coadministration with other… | 7 sources — open the full entry |
| Betamethasone + Phenylephrine + Lignocaine | Moderate | Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics. | 1 sources — open the full entry |
| Bupivacaine Hydrochloride | Moderate | Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics. | 1 sources — open the full entry |
| Bupivacaine Hydrochloride + Dextrose | Moderate | Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics. | 1 sources — open the full entry |
| Calcium Dobesilate + Lidocaine + Dexamethasone | Moderate | Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics. | 1 sources — open the full entry |
| Capmatinib Hydrochloride | Moderate | Metabolism | Coadministration with capmatinib may increase the plasma concentrations and risk of adverse effects of drugs that are substrates of CYP450 1A2. The proposed… | 1 sources — open the full entry |
| Chloramphenicol + Lidocaine Hydrochloride | Moderate | Metabolism · Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics.2 documented mechanisms | 8 sources — open the full entry |
| Cinchocaine + Hydrocortisone + Framycetin + Esculin | Moderate | Synergy | Some topical anesthetics can be systemically absorbed and cause methemoglobinemia, particularly when applied to mucous membranes. Coadministration with other… | 7 sources — open the full entry |
| Cinchocaine + Hydrocortisone + Neomycin + Esculin | Moderate | Synergy | Some topical anesthetics can be systemically absorbed and cause methemoglobinemia, particularly when applied to mucous membranes. Coadministration with other… | 7 sources — open the full entry |
| Clobazam | Moderate | Synergy | The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants. | 7 sources — open the full entry |
| Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine | Moderate | Metabolism | Coadministration with terbinafine may increase the plasma concentrations of drugs that are substrates of the CYP450 2D6 isoenzyme. The mechanism is decreased… | 8 sources — open the full entry |
| Clonazepam | Moderate | Synergy | The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants. | 7 sources — open the full entry |
| Deferasirox | Moderate | Metabolism | Coadministration with deferasirox may increase the plasma concentrations of drugs that are substrates of the CYP450 1A2 isoenzyme. The mechanism is decreased… | 2 sources — open the full entry |
| Diazepam | Moderate | Synergy | The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants. | 7 sources — open the full entry |
| Diclofenac Sodium + Lidocaine Hydrochloride | Moderate | Synergy · Unknown | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics.2 documented mechanisms | 1 sources — open the full entry |
| Flurazepam | Moderate | Synergy | The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants. | 7 sources — open the full entry |
| Fluvoxamine Maleate | Moderate | Metabolism | Coadministration with fluvoxamine may increase the plasma concentrations of ropivacaine. The mechanism is fluvoxamine inhibition of ropivacaine metabolism via… | 11 sources — open the full entry |
| Hydrocortisone + Lidocaine | Moderate | Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics. | 1 sources — open the full entry |
| Hydroxyprogesterone Caproate | Moderate | Metabolism | Coadministration with hydroxyprogesterone may decrease the plasma concentrations of drugs that are metabolized by CYP450 1A2, 2A6, and/or 2B6. | 1 sources — open the full entry |
| Lamivudine + Zidovudine + Nevirapine | Moderate | Metabolism | Coadministration with nevirapine may decrease the plasma concentrations and therapeutic efficacy of drugs that are substrates of CYP450 3A4. The proposed… | 4 sources — open the full entry |
| Lefamulin Acetate | Moderate | Metabolism | When administered orally, lefamulin may increase the plasma concentrations of drugs that are primarily metabolized by CYP450 3A4. Based on interaction with… | 6 sources — open the full entry |
| Lidocaine + Adrenaline | Moderate | Synergy · Unknown | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics.2 documented mechanisms | 1 sources — open the full entry |
| Lidocaine + Epinephrine | Moderate | Synergy · Unknown | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics.2 documented mechanisms | 1 sources — open the full entry |
| Lidocaine HydrochlorideInjectionSpray | Moderate | Synergy | The effect of ropivacaine may be additive when used concomitantly with other amide type local anesthetics. | 1 sources — open the full entry |
| Lidocaine Hydrochloride (Jelly) | Moderate | Synergy | Some topical anesthetics can be systemically absorbed and cause methemoglobinemia, particularly when applied to mucous membranes. Coadministration with other… | 7 sources — open the full entry |
Therapeutic duplication
Drug classes that overlap with Ropivacaine Hydrochloride, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Bupivacaine/lidocaine/triamcinolone
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Epinephrine/prilocaine
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Orabloc
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Scandonest l
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Vivacaine
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Zynrelef
local injectable anesthetics
The recommended maximum number of medicines in the 'local injectable anesthetics' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'local injectable anesthetics' category.
Example product in the source data (US market): Epinephrine/lidocaine