Norepinephrine Tartrate interactions
Checked as Norepinephrine in this data source.
Full monograph for Norepinephrine TartrateCheck it against another medicine
Medicines
124 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Amitriptyline Hydrochloride | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Amitriptyline Hydrochloride + Chlordiazepoxide | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Clomipramine Hydrochloride | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Doxepin (Oral) | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Ergometrine Maleate | Major | Synergy | Additive or synergistic increases in blood pressure and/or ischemic response may occur when ergot alkaloids are combined with peripheral or central… | 38 sources — open the full entry |
| Fluphenazine + Nortriptyline | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Halothane | Major | Others | The combination of norepinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated… | 21 sources — open the full entry |
| Imipramine Hydrochloride | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Isoflurane | Major | Others | The combination of norepinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated… | 21 sources — open the full entry |
| Linezolid | Major | Synergy | Linezolid may potentiate the pressor response to sympathomimetic agents. Linezolid is a reversible, nonselective monoamine oxidase inhibitor (MAOI) and, as… | 24 sources — open the full entry |
| Methylergonovine Maleate | Major | Synergy | Additive or synergistic increases in blood pressure and/or ischemic response may occur when ergot alkaloids are combined with peripheral or central… | 38 sources — open the full entry |
| Nortriptyline | Major | Synergy | Tricyclic antidepressants (TCAs) may markedly enhance the pressor response to parenteral direct-acting sympathomimetic agents and vasoconstrictor-containing… | 11 sources — open the full entry |
| Sevoflurane | Major | Others | The combination of norepinephrine and some anesthetics has resulted in ventricular irritability, serious cardiac arrhythmias, or death. The halogenated… | 21 sources — open the full entry |
| Acarbose | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Aclidinium Bromide + Formoterol Fumarate | Moderate | Synergy | Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists… | 11 sources — open the full entry |
| Alogliptin Benzoate | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Amlodipine Besilate + Atenolol | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Arformoterol Tartrate | Moderate | Synergy | Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists… | 11 sources — open the full entry |
| Atenolol | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Atenolol + Chlorthalidone | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Atomoxetine Hydrochloride | Moderate | Synergy | Central nervous system (CNS) stimulants, particularly the amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic… | 10 sources — open the full entry |
| Beclometasone + Formoterol + Glycopyrronium | Moderate | Synergy | Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists… | 11 sources — open the full entry |
| Beclomethasone Dipropionate + Formoterol Fumarate | Moderate | Synergy | Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists… | 11 sources — open the full entry |
| Betaxolol Hydrochloride | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Bimatoprost + Timolol | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Biphasic Insulin Aspart | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Bisoprolol Fumarate | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Bisoprolol Fumarate + Amlodipine Besilate | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Bisoprolol Fumarate + Hydrochlorothiazide | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Brimonidine Tartrate + Timolol Maleate | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Brinzolamide + Timolol | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Budesonide + Formoterol Fumarate | Moderate | Synergy | Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists… | 11 sources — open the full entry |
| Budesonide + Glycopyrronium Bromide + Formoterol Fumarate | Moderate | Synergy | Coadministration of beta-2 adrenergic agonists with other adrenergic agents may potentiate the risk of cardiovascular side effects. Beta-2 adrenergic agonists… | 11 sources — open the full entry |
| Bupropion Hydrochloride | Moderate | Synergy | Translated with DeepL | 4 sources — open the full entry |
| Canagliflozin Hemihydrate | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Carbidopa + LevodopaExtended releaseProlonged release | Moderate | Synergy | Coadministration with levodopa may potentiate the cardiovascular effects of sympathomimetic agents (e.g., epinephrine, norepinephrine, isoproterenol… | 6 sources — open the full entry |
| Carvedilol | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Dapagliflozin Propanediol | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Desmopressin Acetate | Moderate | Synergy | Concomitant use of vasopressin or desmopressin with catecholamines is expected to result in an additive effect on mean arterial blood pressure and other… | 16 sources — open the full entry |
| Desvenlafaxine Succinate | Moderate | Synergy | Additive or synergistic effects on blood pressure and heart rate may occur when serotonin-norepinephrine reuptake inhibitors (SNRIs) are combined with… | 12 sources — open the full entry |
| Dextromethorphan + Bupropion | Moderate | Synergy | Translated with DeepL | 4 sources — open the full entry |
| Digoxin | Moderate | Synergy | The concomitant use of sympathomimetic agents and cardiac glycosides may increase the risk of cardiac arrhythmias. The mechanism of this interaction is not… | 11 sources — open the full entry |
| Dorzolamide + Timolol | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
| Dulaglutide | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Duloxetine Hydrochloride | Moderate | Synergy | Additive or synergistic effects on blood pressure and heart rate may occur when serotonin-norepinephrine reuptake inhibitors (SNRIs) are combined with… | 12 sources — open the full entry |
| Empagliflozin | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Empagliflozin + Linagliptin | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics…2 documented mechanisms | 95 sources — open the full entry |
| Empagliflozin + Metformin Hydrochloride | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics…2 documented mechanisms | 95 sources — open the full entry |
| Ertugliflozin | Moderate | Antagonism | The efficacy of insulin and other antidiabetic agents may be diminished by certain drugs, including atypical antipsychotics, corticosteroids, diuretics… | 95 sources — open the full entry |
| Esmolol Hydrochloride | Moderate | Antagonism | Beta-blockers may antagonize the cardiostimulatory effects of pressor agents by blocking beta-1 adrenergic receptors in the heart. Vasopressors may be less… | 3 sources — open the full entry |
Conditions
Conditions in which Norepinephrine Tartrate needs care, as documented in this source.
Dehydration
MajorThe use of sympathomimetic amines has been infrequently associated with significant hypotension especially in dehydrated patients secondary to the drug's beta-2 mediated vasodilation. Hypovolemia should be corrected, if possible, before administering sympathomimetic amines. Blood pressure and ECG should be monitored at regular intervals. Monitoring of cardiac output and pulmonary wedge pressure may also be desired.
4 sources
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals (2001):
- "Product Information. Epifrin (EPINEPHrine ophthalmic)." Allergan Inc (2022):
- "Product Information. Adrenalin (EPINEPHrine)." Apothecon Inc (2022):
- "Product Information. Levophed Bitartrate (norepinephrine)." Sanofi Winthrop Pharmaceuticals (2001):
Venous Thromboembolism
MajorNorepinephrine injection should not be given to patients with mesenteric or peripheral vascular thrombosis (because of the risk of increasing ischemia and extending the area of infarction) unless, in the opinion of the attending physician,the administration of norepinephrine is necessary as a life- saving procedure.
1 source
- "Product Information. Levophed (norepinephrine)." Hospira Inc (2017):
Acidosis
ModerateAcidosis, hypoxia, and hypercapnia may reduce the effectiveness of sympathomimetic amines in raising blood pressure. These conditions should be corrected before initiating therapy with sympathomimetic amines, if possible. Monitoring the patients acid-base balance, carbon dioxide levels, and oxygen saturation is recommended.
4 sources
- "Product Information. Isuprel (isoproterenol)." Sanofi Winthrop Pharmaceuticals (2001):
- "Product Information. Epifrin (EPINEPHrine ophthalmic)." Allergan Inc (2022):
- "Product Information. Adrenalin (EPINEPHrine)." Apothecon Inc (2022):
- "Product Information. Levophed Bitartrate (norepinephrine)." Sanofi Winthrop Pharmaceuticals (2001):
Therapeutic duplication
Drug classes that overlap with Norepinephrine Tartrate, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.
sympathomimetic amines
The recommended maximum number of medicines in the 'sympathomimetic amines' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'sympathomimetic amines' category.
Example product in the source data (US market): Guaifenex