Ferrous Ascorbate + Folic Acid + Zinc Sulfate interactions
Checked as Folic acid + Zinc sulfate in this data source.
Full monograph for Ferrous Ascorbate + Folic Acid + Zinc SulfateCheck it against another medicine
Medicines
575 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Capecitabinevia Folic acid | Major | Synergy | Coadministration with folate therapy may potentiate the pharmacologic effects of 5-fluorouracil (5-FU). The exact mechanism of interaction is unknown. Although… | 9 sources — open the full entry |
| Fluorouracilvia Folic acid | Major | Synergy | Coadministration with folate therapy may potentiate the pharmacologic effects of 5-fluorouracil (5-FU). The exact mechanism of interaction is unknown. Although… | 9 sources — open the full entry |
| Alendronic acidvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 9 sources — open the full entry |
| Alendronic Acid + Vitamin D3via Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 9 sources — open the full entry |
| Baloxavir Marboxilvia Zinc sulfate | Moderate | Absorption | Coadministration with polyvalent cation-containing products may decrease the plasma concentrations and therapeutic efficacy of baloxavir. The proposed… | 3 sources — open the full entry |
| Carbamazepinevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Ceftibuten Dihydratevia Zinc sulfate | Moderate | Absorption | Oral products containing zinc such as mineral supplements and multivitamins may interfere with the gastrointestinal absorption of cephalexin, ceftibuten or… | 3 sources — open the full entry |
| Cephalexinvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | Oral products containing zinc such as mineral supplements and multivitamins may interfere with the gastrointestinal absorption of cephalexin, ceftibuten or…2 documented mechanisms | 3 sources — open the full entry |
| Cephradinevia Zinc sulfate | Moderate | Absorption | Oral products containing zinc such as mineral supplements and multivitamins may interfere with the gastrointestinal absorption of cephalexin, ceftibuten or… | 3 sources — open the full entry |
| CiprofloxacinbaseOphthalmicvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Ciprofloxacin + Dexamethasonevia Zinc sulfate, Folic acid | Moderate | Absorption · Antagonism · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…4 documented mechanisms | 36 sources — open the full entry |
| Ciprofloxacin + Hydrocortisone Acetatevia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafinevia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…4 documented mechanisms | 32 sources — open the full entry |
| Deferipronevia Zinc sulfate | Moderate | Absorption | INTERVAL: Deferiprone has the potential to bind polyvalent cations such as aluminum, iron and zinc, which may reduce its effectiveness. However, concurrent use… | 1 sources — open the full entry |
| Delafloxacinvia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics… | 32 sources — open the full entry |
| Dexamethasone + Levofloxacinvia Zinc sulfate, Folic acid | Moderate | Absorption · Antagonism · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…3 documented mechanisms | 36 sources — open the full entry |
| Eltrombopag Olaminevia Zinc sulfate | Moderate | Absorption | INTERVAL: Products containing aluminum, calcium, iron, magnesium, zinc and other polyvalent cations such as antacids or mineral supplements can significantly… | 4 sources — open the full entry |
| Ethosuximidevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Fosphenytoin Sodiumvia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Gatifloxacinvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Gatifloxacin + Dexamethasonevia Zinc sulfate, Folic acid | Moderate | Absorption · Antagonism · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…4 documented mechanisms | 36 sources — open the full entry |
| Gemifloxacinvia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics… | 32 sources — open the full entry |
| Ibandronic Acidvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 9 sources — open the full entry |
| Ibandronic Acid + Algae Calcium + Vitamin D3via Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 9 sources — open the full entry |
| Ibandronic Acid + Coral Calcium + Vitamin D3via Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 9 sources — open the full entry |
| Lamotriginevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Levofloxacin (Eye/Ear)via Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics… | 32 sources — open the full entry |
| Levofloxacin Hemihydratevia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics… | 32 sources — open the full entry |
| Lomefloxacinvia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics… | 32 sources — open the full entry |
| Loteprednol Etabonate + Gatifloxacinvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Methotrexatevia Folic acid | Moderate | Antagonism | Coadministration of methotrexate with vitamin preparations containing folic acid, folinic acid (leucovorin) or their derivatives may diminish the therapeutic… | 4 sources — open the full entry |
| Minocycline Hydrochloridevia Zinc sulfate | Moderate | Absorption | INTERVAL: The bioavailability of oral tetracyclines may be significantly decreased during concurrent administration with zinc-containing products. Therapeutic… | 7 sources — open the full entry |
| Moxifloxacin HydrochlorideInjectionOphthalmicTabletvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Moxifloxacin Hydrochloride + Dexamethasonevia Zinc sulfate, Folic acid | Moderate | Absorption · Antagonism · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…4 documented mechanisms | 36 sources — open the full entry |
| Moxifloxacin Hydrochloride + Xanthan Gumvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Nalidixic Acidvia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of nalidixic acid… | 1 sources — open the full entry |
| Ofloxacinvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…2 documented mechanisms | 32 sources — open the full entry |
| Ofloxacin + Clotrimazole + Beclomethasone + Lidocainevia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics…4 documented mechanisms | 32 sources — open the full entry |
| Oxcarbazepinevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Oxytetracyclinevia Zinc sulfate | Moderate | Absorption | INTERVAL: The bioavailability of oral tetracyclines may be significantly decreased during concurrent administration with zinc-containing products. Therapeutic… | 7 sources — open the full entry |
| Oxytetracycline + Polymixin B Sulphatevia Zinc sulfate | Moderate | Absorption | INTERVAL: The bioavailability of oral tetracyclines may be significantly decreased during concurrent administration with zinc-containing products. Therapeutic… | 7 sources — open the full entry |
| Penicillaminevia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral administration of aluminum, copper, iron, zinc, magnesium, and possibly other minerals such as calcium may decrease the gastrointestinal… | 7 sources — open the full entry |
| Phenobarbitalvia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Phenytoin Sodiumvia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Primidonevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Risedronate Sodiumvia Zinc sulfate, Folic acid | Moderate | Absorption · Unknown | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 9 sources — open the full entry |
| Sodium Valproatevia Folic acid | Moderate | Antagonism | Anticonvulsants including, but not limited to, carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid have been shown to impair… | 26 sources — open the full entry |
| Sparfloxacinvia Zinc sulfate | Moderate | Absorption | INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the gastrointestinal absorption of quinolone antibiotics… | 32 sources — open the full entry |
| Sulphadoxine + Pyrimethaminevia Folic acid | Moderate | Antagonism | Folate antagonists such as sulfonamides, triamterene, trimethoprim, or pyrimethamine may decrease folic acid serum concentration. The mechanism may be related…2 documented mechanisms | 22 sources — open the full entry |
| Sulphamethoxazole + Trimethoprimvia Folic acid | Moderate | Antagonism | Folate antagonists such as sulfonamides, triamterene, trimethoprim, or pyrimethamine may decrease folic acid serum concentration. The mechanism may be related…2 documented mechanisms | 22 sources — open the full entry |
Food & lifestyle
alcohol
ModerateSynergy
Ethanol may increase folic acid elimination and folic acid absorption is decreased in chronic alcoholics. Excessive alcohol consumption may lead to folate deficiency.
What to do: Monitoring of patient response to folic acid supplementation if they also consume alcohol regularly may be recommended.
5 sources
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia Espa?ola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaci��n online de medicamentos de la AEMPS - CIMA. https://cima.aemps.es/cima/publico/home.html" (2008):
- Cerner Multum, Inc "ANVISA Bul��rio Eletr?nico." O 0 (2015):
- "Product Information. Folic Acid (folic acid)." Method Pharmaceuticals, LLC (2017):
Conditions
Conditions in which Ferrous Ascorbate + Folic Acid + Zinc Sulfate needs care, as documented in this source.
Anemia
MajorThe use of folic acid is contraindicated in patients with undiagnosed anemia. Folic acid in dosages above 1 mg/day can obscure the diagnosis of pernicious anemia by alleviating the hematologic abnormalities while allowing the progression of neurologic complications. In addition, folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.
3 sources
- Butterworth CE Jr, Tamura T "Folic acid safety and toxicity: a brief review." Am J Clin Nutr 50 (1989): 353-8
- Katz M "Potential danger of self-medication with folic acid." N Engl J Med 289 (1973): 1095
- "Product Information. Renal Multivitamin Formula Rx (folic acid)." Vitaline Corporation, Ashland, OR.
Kidney Diseases
ModerateThe trace metals, chromium and zinc, are excreted primarily in the urine. Selenium is partially excreted in the urine. Supplemental doses of these agents may need to be adjusted, reduced, or omitted in patients with renal dysfunction.
3 sources
- "Product Information. Galzin (zinc acetate)." Teva Pharmaceuticals USA (2001):
- "Product Information. Chroma-Pak (chromic chloride hexahydrate)." Apothecon Inc (2022):
- "Product Information. Sele-Pak (selenium)." Fujisawa
Malabsorption Syndromes
ModerateThe trace metals manganese, chromium, copper, selenium, and zinc are absorbed in the GI tract from dietary sources and following administration of oral supplements. GI absorption may be decreased in patients with malabsorption syndromes. Therefore, larger dosages may be required when these supplements are given orally. Parenteral administration may be appropriate.
6 sources
- "Product Information. Galzin (zinc acetate)." Teva Pharmaceuticals USA (2001):
- "Product Information. Chroma-Pak (chromic chloride hexahydrate)." Apothecon Inc (2022):
- "Product Information. Sele-Pak (selenium)." Fujisawa
- "Product Information. Copper Sulfate (copper sulfate)." Humco Holding Group (2001):
- "Product Information. Manganese Chloride (manganese chloride)." Abbott Pharmaceutical (2001):
- "Product Information. Manganese Sulfate (manganese sulfate)." American Regent Laboratories Inc (2001):