Skip to content
Med Rx.

Cloxacillin Sodium interactions

Checked as Cloxacillin in this data source.

Full monograph for Cloxacillin SodiumCheck it against another medicine

Medicines

37 documented

Medicines documented to interact with Cloxacillin Sodium, worst severity first.
MedicineSeverityMechanismEffectSources
MethotrexateMajorExcretionConcomitant use of large doses of penicillins may elevate serum methotrexate concentrations. The mechanism may involve competitive inhibition of renal tubular…11 sources — open the full entry
Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + LidocaineModerateAntagonismChloramphenicol may inhibit the bactericidal effect of penicillins when used to treat bacterial meningitis and staphylococcal endocarditis. Chloramphenicol…4 sources — open the full entry
Chloramphenicol (Oral)ModerateAntagonismChloramphenicol may inhibit the bactericidal effect of penicillins when used to treat bacterial meningitis and staphylococcal endocarditis. Chloramphenicol…4 sources — open the full entry
Chloramphenicol + Lidocaine HydrochlorideModerateAntagonismChloramphenicol may inhibit the bactericidal effect of penicillins when used to treat bacterial meningitis and staphylococcal endocarditis. Chloramphenicol…4 sources — open the full entry
Cyproterone Acetate + Ethinyl EstradiolModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Dexamethasone + ChloramphenicolModerateAntagonismChloramphenicol may inhibit the bactericidal effect of penicillins when used to treat bacterial meningitis and staphylococcal endocarditis. Chloramphenicol…4 sources — open the full entry
Dienogest + Estradiol ValerateModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Doxycycline HydrochlorideModerateAntagonismTetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by…8 sources — open the full entry
Drospirenone + EstradiolModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Drospirenone + Ethinyl Estradiol0.02 mg0.03 mgModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Drospirenone + Ethinyl Estradiol + LevomefolateModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Entecavir MonohydrateModerateExcretionCoadministration of entecavir with another drug that is also eliminated by active tubular secretion may result in increased plasma concentrations of one or…2 sources — open the full entry
Estradiolbasevaginal creamModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Estradiol + DydrogesteroneModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Estradiol Hemihydrate + Progesterone MicronizedModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Estradiol ValerateModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Ethinyl Estradiol + Desogestrel0.02 mg0.03 mgModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Ethinyl Estradiol + GestodeneModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Ethinyl Estradiol + Levonorgestrel + Ferrous FumarateModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Ethinyl Estradiol + Lynestrenol0.0375 mg0.05 mgModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Minocycline HydrochlorideModerateAntagonismTetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by…8 sources — open the full entry
Mycophenolate MofetilModerateAbsorptionTheoretically, drugs that alter the gastrointestinal flora (e.g., antibiotics) may reduce the oral bioavailability of mycophenolic acid products. Some…3 sources — open the full entry
Mycophenolic acidModerateAbsorptionTheoretically, drugs that alter the gastrointestinal flora (e.g., antibiotics) may reduce the oral bioavailability of mycophenolic acid products. Some…3 sources — open the full entry
Norgestrel + Ethinyl Estradiol + Ferrous FumarateModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
OxytetracyclineModerateAntagonismTetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by…6 sources — open the full entry
Oxytetracycline + Polymixin B SulphateModerateAntagonismTetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by…6 sources — open the full entry
PemetrexedModerateExcretionCoadministration with drugs that are eliminated by active tubular secretion may delay and/or decrease the clearance of pemetrexed. The mechanism is competitive…1 sources — open the full entry
Relugolix + Estradiol + NorethindroneModerateAntagonismRECOMMENDED: The effectiveness of estrogen-containing oral contraceptives may be impaired by concomitant treatment with antimicrobial agents. Most…38 sources — open the full entry
Tetracycline HydrochlorideModerateAntagonismTetracyclines may reduce the effect of penicillins by inhibiting cellular protein synthesis which is necessary for cell wall synthesis inhibition by…8 sources — open the full entry
Warfarin SodiumModerateSynergyPenicillins may occasionally potentiate the risk of bleeding in patients treated with oral anticoagulants. The exact mechanism of interaction is unknown but…54 sources — open the full entry
Azithromycin DihydratebaseOphthalmicMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry
ClarithromycinMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry
ErythromycinLotionOralMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry
Esomeprazole + Amoxicillin + ClarithromycinMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry
Lansoprazole + Amoxicillin + ClarithromycinMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry
Rabeprazole + Amoxicillin + ClarithromycinMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry
Vonoprazan + Amoxicillin + ClarithromycinMinorOthersAlthough some in vitro data indicate synergism between macrolide antibiotics and penicillins, other in vitro data indicate antagonism. When these drugs are…3 sources — open the full entry

Therapeutic duplication

Drug classes that overlap with Cloxacillin Sodium, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.