Vecuronium Bromide interactions

Checked as Vecuronium in this data source.

Full monograph for Vecuronium Bromide Check it against another medicine

Medicines

282 documented

Severity

Mechanism

Medicines documented to interact with Vecuronium Bromide, worst severity first.
Medicine	Severity	Mechanism	Effect	Sources
Amikacin	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Bacitracin Zinc + Polymyxin B Sulfate	Major	Others · Synergy	Polymyxin B may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular…2 documented mechanisms	5 sources — open the full entry
Betamethasone + Clotrimazole + Gentamicin	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Betamethasone + Neomycin Sulphate (Ophthalmic)	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Cinchocaine + Hydrocortisone + Framycetin + Esculin	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Cinchocaine + Hydrocortisone + Neomycin + Esculin	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Clobetasol Propionate + Neomycin Sulphate + Nystatin	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Colistimethate Sodium	Major	Synergy	Like other polypeptide antibiotics, colistimethate may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be…	10 sources — open the full entry
Dexamethasone + Neomycin + Glacial Acetic Acid	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Dexamethasone + Neomycin Sulphate + Polymyxin B Sulphate	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…3 documented mechanisms	27 sources — open the full entry
Dexamethasone + Tobramycin	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Fluocinolone Acetonide + Neomycin Sulfate	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Fluormetholone + Neomycin Sulphate	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Fluorometholone + Gentamicin	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Gentamicin + Hydrocortisone Acetate	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Gentamicin SulfateInjection Ophthalmic	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Gramacidin + Neomycin + Polymixin B	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	20 sources — open the full entry
Hydrocortisone + Neomycin Sulphate + Polymixin B	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…3 documented mechanisms	27 sources — open the full entry
Hydrocortisone Acetate + Neomycin Sulphate	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Kanamycin	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Loteprednol Etabonate + Tobramycin	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Metronidazole + Neomycin Sulphate + Polymyxin B + Nystatin	Major	Others · Synergy · Unknown	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…3 documented mechanisms	20 sources — open the full entry
Neomycin Sulfate + Bacitracin Zinc	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	19 sources — open the full entry
Neomycin Sulfate + Bacitracin Zinc + Polymyxin B Sulfate	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…3 documented mechanisms	22 sources — open the full entry
Neomycin Sulphate + Polymyxin B Sulphate + Pramoxine	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	20 sources — open the full entry
Oxytetracycline + Polymixin B Sulphate	Major	Others · Synergy	Polymyxin B may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular…2 documented mechanisms	5 sources — open the full entry
Polymyxin B Sulfate	Major	Others	Polymyxin B may prolong apnea and respiratory paralysis after use of neuromuscular blocking agents. The mechanism may be related to decreased intracellular…	3 sources — open the full entry
Prednisolone + Neomycin Sulphate + Polymixin B Sulphate	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…3 documented mechanisms	27 sources — open the full entry
TobramycinNebuliser Solution Ophthalmic	Major	Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…	17 sources — open the full entry
Triamcinolone + Neomycin + Nystatin + Gramicidin	Major	Others · Synergy	Aminoglycosides possess neuromuscular blocking activity, which may be additive with that of depolarizing and nondepolarizing muscle relaxants, potentially…2 documented mechanisms	24 sources — open the full entry
Acetazolamide	Moderate	Synergy	Diuretics may induce hypokalemia and prolong the neuromuscular blocking effects of nondepolarizing muscle relaxants.	4 sources — open the full entry
Acyclovir + Hydrocortisone	Moderate	Others · Unknown	Corticosteroids may inhibit or enhance the action of nondepolarizing skeletal muscle relaxants. The mechanism is unknown. In addition, the risk of myopathy may…2 documented mechanisms	7 sources — open the full entry
Alprazolam	Moderate	Others	Benzodiazepines may have variable effects on nondepolarizing muscle relaxants. Potentiation, attenuation, and no effect have all been reported.	9 sources — open the full entry
Aminophylline	Moderate	Antagonism	Methylxanthines may antagonize the effects of neuromuscular blockers. The mechanism is unknown. In patients stabilized on aminophylline, resistance to…	3 sources — open the full entry
Amitriptyline Hydrochloride + Chlordiazepoxide	Moderate	Others	Benzodiazepines may have variable effects on nondepolarizing muscle relaxants. Potentiation, attenuation, and no effect have all been reported.	9 sources — open the full entry
Amlodipine Besilate	Moderate	Synergy	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…	36 sources — open the full entry
Amlodipine Besilate + Atenolol	Moderate	Synergy	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…2 documented mechanisms	44 sources — open the full entry
Amlodipine Besilate + Atorvastatin	Moderate	Synergy	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…	36 sources — open the full entry
Amlodipine Besilate + Benazepril Hydrochloride	Moderate	Synergy	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…	36 sources — open the full entry
Amlodipine Besilate + Olmesartan Medoxomil	Moderate	Synergy	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…	36 sources — open the full entry
Amlodipine Besilate + Telmisartan	Moderate	Synergy	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…	36 sources — open the full entry
Amlodipine Besilate + Valsartan	Moderate	Synergy · Unknown	Some calcium channel blockers may enhance the neuromuscular blocking properties of nondepolarizing muscle relaxants. The mechanism is not known, but may…2 documented mechanisms	36 sources — open the full entry
Amphotericin B	Moderate	Excretion	Amphotericin commonly causes renal potassium and magnesium wasting. As a result, serum potassium is decreased, and the pharmacologic effects of some…	4 sources — open the full entry
Atenolol	Moderate	Synergy	Neuromuscular blocking agents and beta-blockers may have additive cardiovascular depressant effects. Limited data suggest that beta-blockers may modestly…	8 sources — open the full entry
Atenolol + Chlorthalidone	Moderate	Synergy	Neuromuscular blocking agents and beta-blockers may have additive cardiovascular depressant effects. Limited data suggest that beta-blockers may modestly…2 documented mechanisms	12 sources — open the full entry
Atracurium Besilate	Moderate	Synergy	When combined with vecuronium, other nondepolarizing neuromuscular blocking agents may have additive effects or modifying influences.	3 sources — open the full entry
Azilsartan Medoxomil + Chlorthalidone	Moderate	Synergy	Diuretics may induce hypokalemia and prolong the neuromuscular blocking effects of nondepolarizing muscle relaxants.	4 sources — open the full entry
Beclomethasone Dipropionate + Chloramphenicol + Clotrimazole + Lidocaine	Moderate	Synergy	Lidocaine may enhance the effect of neuromuscular blocking agents. The mechanism is not known, but may include inhibition of acetylcholine release from…	6 sources — open the full entry
Betamethasone	Moderate	Others	Corticosteroids may inhibit or enhance the action of nondepolarizing skeletal muscle relaxants. The mechanism is unknown. In addition, the risk of myopathy may…	7 sources — open the full entry
Betamethasone + Calcipotriol	Moderate	Others	Corticosteroids may inhibit or enhance the action of nondepolarizing skeletal muscle relaxants. The mechanism is unknown. In addition, the risk of myopathy may…	7 sources — open the full entry

Conditions

Conditions in which Vecuronium Bromide needs care, as documented in this source.

Liver Diseases
Major
Neuromuscular blocking agents undergo metabolism by the liver. Elimination and effects may be prolonged in patients with liver disease. Therapy with neuromuscular blocking agents should be administered cautiously in patients with liver disease.
5 sources
1. "Product Information. Zemuron (rocuronium)." Organon (2001):
2. "Product Information. Mivacron (mivacurium)." Glaxo Wellcome (2001):
3. "Product Information. Nuromax (doxacurium)." Glaxo Wellcome (2001):
4. "Product Information. Norcuron (vecuronium)." Organon (2001):
5. "Product Information. Metubine Iodide (metocurine)." Dista Products Company (2001):
Paresis
Major
Patients with hemiparesis or paraparesis may require higher dosages of non-depolarizing neuromuscular blocking agents in the affected limbs. Neuromuscular monitoring should be performed on a non-paretic limb to avoid inaccurate dosing.
6 sources
1. "Product Information. Zemuron (rocuronium)." Organon (2001):
2. "Product Information. Mivacron (mivacurium)." Glaxo Wellcome (2001):
3. "Product Information. Nuromax (doxacurium)." Glaxo Wellcome (2001):
4. "Product Information. Tracrium (atracurium)." Glaxo Wellcome (2001):
5. "Product Information. Norcuron (vecuronium)." Organon (2001):
6. "Product Information. Metubine Iodide (metocurine)." Dista Products Company (2001):
Respiratory Insufficiency
Major
Neuromuscular blocking agents can cause respiratory depression and paralysis. Therapy with neuromuscular blocking agents should be administered cautiously in patients with pulmonary impairment. Treatment of respiratory paralysis consists of positive-pressure artificial respiration with oxygen and maintenance of a patent airway until the recovery of normal respiration is assured.
7 sources
1. "Product Information. Zemuron (rocuronium)." Organon (2001):
2. "Product Information. Anectine (succinylcholine)." Glaxo Wellcome (2001):
3. "Product Information. Mivacron (mivacurium)." Glaxo Wellcome (2001):
4. "Product Information. Nuromax (doxacurium)." Glaxo Wellcome (2001):
5. "Product Information. Tracrium (atracurium)." Glaxo Wellcome (2001):
6. "Product Information. Norcuron (vecuronium)." Organon (2001):
7. "Product Information. Metubine Iodide (metocurine)." Dista Products Company (2001):

Medicines

Conditions

Liver Diseases

Paresis

Respiratory Insufficiency