Magnesium Hydroxide interactions
Full monograph for Magnesium HydroxideCheck it against another medicine
Medicines
354 documented
| Medicine | Severity | Mechanism | Effect | Sources |
|---|---|---|---|---|
| Erdafitinib | Major | Others | Coadministration with agents that can alter serum phosphate levels may affect the initial dosage determination of erdafitinib. The mechanism appears to be… | 1 sources — open the full entry |
| Gefitinib | Major | Absorption | Coadministration with drugs that elevate gastric pH such as H2-receptor antagonists and antacids may decrease the plasma concentrations of gefitinib. According… | 5 sources — open the full entry |
| Selpercatinib | Major | Absorption | Coadministration with drugs that increase gastric pH may significantly decrease the oral bioavailability of selpercatinib and reduce its concentrations in… | 2 sources — open the full entry |
| Sotorasib | Major | Absorption | Coadministration with drugs that increase gastric pH may significantly decrease the oral bioavailability of sotorasib and reduce its concentrations in plasma. | 2 sources — open the full entry |
| Abiraterone Acetate | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Acalabrutinib | Moderate | Absorption | INTERVAL: Coadministration with drugs that increase gastric pH may significantly decrease the oral bioavailability of acalabrutinib and reduce its… | 2 sources — open the full entry |
| Acetazolamide | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Acyclovir + Hydrocortisone | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Alendronic acid | Moderate | Absorption | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to… | 9 sources — open the full entry |
| Alendronic Acid + Vitamin D3 | Moderate | Absorption · Synergy | INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to…2 documented mechanisms | 13 sources — open the full entry |
| Alfuzosin Hydrochloride | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Algae Calcium + Vitamin D3 | Moderate | Synergy | Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to… | 4 sources — open the full entry |
| Aluminium Oxide + Magnesium Trisilicate | Moderate | Synergy | The concomitant administration of magnesium salts with other magnesium-containing preparations such as antacids or laxatives may increase the risk of magnesium… | 1 sources — open the full entry |
| Amiodarone Hydrochloride | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Amisulpride | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Apalutamide | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Arsenic Trioxide | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Artemether + Lumefantrine | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…2 documented mechanisms | 12 sources — open the full entry |
| Asciminib | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Asenapine Maleate | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Aspirin | Moderate | Excretion | Chronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism… | 8 sources — open the full entry |
| Aspirin + Dipyridamole | Moderate | Excretion | Chronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism… | 8 sources — open the full entry |
| Atenolol + Chlorthalidone | Moderate | Absorption · Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…2 documented mechanisms | 12 sources — open the full entry |
| Atomoxetine Hydrochloride | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Atropine Sulfate (Injection) | Moderate | Absorption | INTERVAL: Concurrent administration of antacids or adsorbent antidiarrheal agents may decrease the oral bioavailability of atropine. | 1 sources — open the full entry |
| Azilsartan Medoxomil + Chlorthalidone | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Azithromycin DihydratebaseOphthalmic | Moderate | Absorption | INTERVAL: The concomitant administration of aluminum or magnesium-containing antacids may reduce peak serum concentrations (Cmax) of oral azithromycin, but… | 1 sources — open the full entry |
| Baloxavir Marboxil | Moderate | Absorption | Coadministration with polyvalent cation-containing products may decrease the plasma concentrations and therapeutic efficacy of baloxavir. The proposed… | 3 sources — open the full entry |
| Benzoic Acid + Salicylic Acid | Moderate | Excretion | Chronic administration of antacids may reduce serum salicylate concentrations in patients receiving large doses of aspirin or other salicylates. The mechanism… | 8 sources — open the full entry |
| Betamethasone | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone + Calcipotriol | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone + Clotrimazole | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone + Clotrimazole + Gentamicin | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone + Neomycin Sulphate (Ophthalmic) | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone + Phenylephrine + Lignocaine | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone Dipropionate | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone Dipropionate + Salicylic Acid | Moderate | Antagonism · Excretion | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…2 documented mechanisms | 15 sources — open the full entry |
| Betamethasone Sodium Phosphate | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Betamethasone Valerate | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Bicalutamide | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Bisacodyl | Moderate | Absorption | INTERVAL: By increasing gastric pH, antacids may reduce the resistance of the enteric coating of bisacodyl tablets, resulting in earlier release of bisacodyl… | 1 sources — open the full entry |
| Bisoprolol Fumarate + Hydrochlorothiazide | Moderate | Absorption · Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…2 documented mechanisms | 12 sources — open the full entry |
| Bumetanide | Moderate | Synergy | The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes… | 5 sources — open the full entry |
| Cabozantinib | Moderate | Synergy | Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… | 6 sources — open the full entry |
| Calcitriol | Moderate | Synergy | Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to… | 4 sources — open the full entry |
| Calcium + Vitamin D3 + Multimineral | Moderate | Synergy | Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to… | 4 sources — open the full entry |
| Calcium acetate + Magnesium carbonate | Moderate | Synergy | The concomitant administration of magnesium salts with other magnesium-containing preparations such as antacids or laxatives may increase the risk of magnesium… | 1 sources — open the full entry |
| Calcium Citrate + Calcitriol | Moderate | Synergy | Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to… | 4 sources — open the full entry |
| Calcium Dobesilate + Lidocaine + Dexamethasone | Moderate | Antagonism | The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… | 7 sources — open the full entry |
| Calcium Lactate Gluconate + Calcium Carbonate + Vitamin C + Vitamin D3 | Moderate | Synergy | Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to… | 4 sources — open the full entry |
Conditions
Conditions in which Magnesium Hydroxide needs care, as documented in this source.
Inflammatory Bowel Diseases
MajorThe use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
6 sources
- "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc (2001):
- "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
- "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
- "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc (2001):
- "Product Information. SenoSol-X (senna)." Apothecon Inc (2022):
- "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories (2010):
Intestinal Obstruction
MajorThe use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
8 sources
- "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc (2001):
- "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
- "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
- "Product Information. Fleet Mineral Oil Enema (mineral oil)." Fleet (2001):
- "Product Information. Citrucel (methylcellulose)." SmithKline Beecham (2001):
- "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc (2001):
- "Product Information. SenoSol-X (senna)." Apothecon Inc (2022):
- "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories (2010):
Kidney Diseases
MajorMagnesium is eliminated by the kidney. The serum concentration of magnesium is increased in patients with renal impairment. Magnesium toxicity includes CNS depression, muscular paralysis, respiratory depression, hypotension and prolonged cardiac conduction time. Disappearance of the patellar reflex is a useful clinical sign of magnesium intoxication. Therapy with magnesium should be administered cautiously and dosages should be modified in patients with compromised renal function. Clinical monitoring of serum magnesium levels is recommended.
5 sources
- "Product Information. Mag-Ox 400 (magnesium oxide)." Blaine Company Inc. (2001):
- "Product Information. Uro-Mag (magnesium oxide)." Blaine Company Inc. (2001):
- "Product Information. Slow-Mag (magnesium chloride)." Searle (2001):
- "Product Information. Magonate (magnesium gluconate)." Fleming and Company (2001):
- "Product Information. Losospan (magaldrate)." Whitehall-Robbins (2001):
Therapeutic duplication
Drug classes that overlap with Magnesium Hydroxide, so taking both doubles up the same effect. This source publishes no per-row citations for duplication.
stimulant and hyperosmotic laxat
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category.
Example product in the source data (US market): Urolet mb
stimulant and hyperosmotic laxat
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category.
Example product in the source data (US market): Phosphasal
stimulant and hyperosmotic laxat
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category.
Example product in the source data (US market): Suprep bowel prep kit
stimulant and hyperosmotic laxat
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category.
Example product in the source data (US market): Sutab
stimulant and hyperosmotic laxat
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category.
Example product in the source data (US market): Prepopik
stimulant and hyperosmotic laxat
The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one.Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category.
Example product in the source data (US market): Mannitol/sorbitol (topical)