Glycerol + Hypromellose + Polyethylene Glycol 400 interactions

Checked as Glycerin in this data source.

Full monograph for Glycerol + Hypromellose + Polyethylene Glycol 400 Check it against another medicine

Medicines

197 documented

Severity

Mechanism

Medicines documented to interact with Glycerol + Hypromellose + Polyethylene Glycol 400, worst severity first.
Medicine	Severity	Mechanism	Effect	Sources
Abiraterone Acetate	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Acetazolamide	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Acyclovir + Hydrocortisone	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Alfuzosin Hydrochloride	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Amiodarone Hydrochloride	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Amisulpride	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Amlodipine Besilate + Benazepril Hydrochloride	Moderate	Synergy	Although they are frequently combined in clinical practice, diuretics and angiotensin converting enzyme (ACE) inhibitors may have additive effects…	26 sources — open the full entry
Apalutamide	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Arsenic Trioxide	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Artemether + Lumefantrine	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in… 2 documented mechanisms	12 sources — open the full entry
Asciminib	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Asenapine Maleate	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Atenolol + Chlorthalidone	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Atomoxetine Hydrochloride	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Azilsartan Medoxomil + Chlorthalidone	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Azithromycin Dihydrate base Ophthalmic	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Betamethasone	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone + Calcipotriol	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone + Clotrimazole	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone + Clotrimazole + Gentamicin	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone + Neomycin Sulphate (Ophthalmic)	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone + Phenylephrine + Lignocaine	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone Dipropionate	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone Dipropionate + Salicylic Acid	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone Sodium Phosphate	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Betamethasone Valerate	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Bicalutamide	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Bisoprolol Fumarate + Hydrochlorothiazide	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Bumetanide	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Cabozantinib	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Calcium Dobesilate + Lidocaine + Dexamethasone	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Candesartan Cilexetil + Hydrochlorothiazide	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Captopril	Moderate	Synergy	Although they are frequently combined in clinical practice, diuretics and angiotensin converting enzyme (ACE) inhibitors may have additive effects…	26 sources — open the full entry
Carbamazepine	Moderate	Synergy	Carbamazepine may cause clinically significant hyponatremia. Data show that the risk of hyponatremia may be additive when carbamazepine and hydrochlorothiazide…	5 sources — open the full entry
Ceritinib	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Chlorpromazine Hydrochloride	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Chlorthalidone	Moderate	Synergy	The chronic use or abuse of laxatives may potentiate the pharmacologic effects of diuretics. Laxatives can cause significant losses of fluid and electrolytes…	5 sources — open the full entry
Cilostazol	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Cinchocaine + Hydrocortisone + Framycetin + Esculin	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Cinchocaine + Hydrocortisone + Neomycin + Esculin	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Ciprofloxacin base Ophthalmic	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Ciprofloxacin + Dexamethasone	Moderate	Antagonism · Synergy	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy… 2 documented mechanisms	13 sources — open the full entry
Ciprofloxacin + Hydrocortisone Acetate	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Citalopram Hydrobromide	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Clarithromycin	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Clotrimazole + Hydrocortisone	Moderate	Antagonism	The overuse or abuse of laxatives can cause significant loss of electrolytes and potentiate the risk of hypokalemia associated with corticosteroid therapy…	7 sources — open the full entry
Clozapine	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Crizotinib	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry
Dasatinib	Moderate	Synergy	Bowel cleansing as well as overuse of certain laxatives may cause electrolyte loss and increase the risk of torsade de pointes ventricular arrhythmia in…	6 sources — open the full entry

Conditions

Conditions in which Glycerol + Hypromellose + Polyethylene Glycol 400 needs care, as documented in this source.

Inflammatory Bowel Diseases
Major

The use of laxatives is contraindicated in patients with inflammatory bowel disease. Patients with inflammatory bowel disease may experience colonic perforation with use of stimulant laxatives.
6 sources
1. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc (2001):
2. "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
3. "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
4. "Product Information. Neoloid (castor oil)." Paddock Laboratories Inc (2001):
5. "Product Information. SenoSol-X (senna)." Apothecon Inc (2022):
6. "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories (2010):
Intestinal Obstruction
Major

The use of laxatives is contraindicated in patients with intestinal obstruction disorders. Patients with intestinal obstruction disorders may need their underlying condition treated to correct the constipation. Some laxatives require reduction in the colon to their active form to be effective which may be a problem in patients with intestinal obstruction.
8 sources
1. "Product Information. Dulcolax (bisacodyl)." Ciba Self-Medication Inc (2001):
2. "Product Information. Fleet Bisacodyl (bisacodyl)." Fleet
3. "Product Information. Kondremul Plain (mineral oil)." Bristol-Myers Squibb
4. "Product Information. Fleet Mineral Oil Enema (mineral oil)." Fleet (2001):
5. "Product Information. Citrucel (methylcellulose)." SmithKline Beecham (2001):
6. "Product Information. Fleet Babylax (glycerin)." Alcon Laboratories Inc (2001):
7. "Product Information. SenoSol-X (senna)." Apothecon Inc (2022):
8. "Product Information. Suprep Bowel Prep Kit (magnesium/potassium/sodium sulfates)." Braintree Laboratories (2010):

Medicines

Conditions

Inflammatory Bowel Diseases

Intestinal Obstruction