Ethanol + Isopropyl alcohol + Nicotinic Acid [Niacin]
Moderate
1 published source
This interaction is documented in this data source.
- Ethanol + Isopropyl alcohol
- Checked as Ethanol
- Nicotinic Acid [Niacin]
- Checked as Niacin
What is documented
-
Synergy
Moderatevia Ethanol and Niacin
What happens
Ethanol can exacerbate the cutaneous flushing that is a common side effect of niacin. At least one case of delirium and lactic acidosis has been reported with coadministration of these drugs, although data are limited.
What to do
Coadministration should probably be discouraged, particularly since chronic consumption of large amounts of alcohol is associated with hyperlipidemia.
1 source
- Schwab RA, Bachhuber BH "Delirium and lactic acidosis caused by ethanol and niacin coingestion." Am J Emerg Med 9 (1991): 363-5